INDEX Nerve Conduction Local Anaesthetics Nerve Conduction The Cleveland Clinic Foundation has a good description of Basic Nerve Physiology which is aimed at anaesthetists. It includes a detailed discussion about the mechanism of action of local anaesthetics. Local Anaesthetics I have established an Internet discussion list about local anaesthetics and regional anaesthesia. To subscribe, send "subscribe lara-l (yourname)" as the text of a message with no subject and no signature, to LISTSERV@GROUCHO.MED.YALE.EDU. Further information about this list is available on the Web. World Anaesthesia and the World Federation of Societies of Anaesthesiologists have published an excellent article on "The Pharmacology of Local Anaesthetic Agents" as part of "Update in Anaesthesia", a journal for anaesthetists in developing countries. Allan Palmer has set up a slide show on Local Anaesthetics. It includes some very clear images but can be slow to download. The Cleveland Clinic Foundation Department of Anaesthesia site includes a useful section on the Pharmacology of Local Anaesthetics, with sections on their properties , toxicity, and on specific ester and amide anaesthetics. The site also includes advice on choosing a local anaesthetic based on the experience of their orthopaedic anaesthetists. Gasbone includes a brief description of local anaesthetic drugs. Specific Drugs  Bupivacaine Structural Formula A copy of the Physicians Desk Reference section on Bupivacaine. Overview for professionals and for the public by paediatric nurses. Toxicity Spinal Anesthesia With 0.5% S(–)-Bupivacaine for Elective Lower Limb Surgery  Lidocaine Lidocaine spinal anaesthesia. The end of an era? ESRA 1998 abstract  Mepivacaine Structural formula. General information  Ropivacaine Vancouver pharmacy description (1998) Structural formula, Ropivacaine in Obstetric Anaesthesia by Stephen Gatt, and Experience with Ropivacaine for labour analgesia by Genevieve Goulding, all parts of Manbit, from about 1995 Regional Anesthesia with Ropivacaine, a collection of abstracts. Ropivacaine for Surgical Anesthesia by Spencer S Liu Ropivacaine in peripheral blocks, Ropivacaine in obsetrics part of the ESRA 1998 abstracts. Comparison with Bupivacaine for Axillary Block Ropivacaine in post-operative pain management by Dr Finucaune, 1998 Astra Pharma Inc has a home page, but it does not contain clinical information. The Virtual Textbook of Anaesthesia includes a related chapter on "Local and Regional Anaesthetic Techniques". You are visitor number since April 29th 2000. Please direct all comments on organization of this chapter, corrections to links, and suggestions for additions to: . Revised May 2000. Questions about the Virtual Anaesthetic Textbook project should be sent to Dr. Thompson on this form.